Clinical papers

LARS ligaments have been in clinical use for over 15 years and have demonstrated outcomes comparable with existing autograft and allograft results in over thousands of intra-articular cases. Unlike former generations of synthetic ligaments, no increased incidence of foreign body reaction or any other adverse reaction has been reported in literature. A large number of published papers in international journals, multiple book chapters and congress abstracts show that LARS ligament procedures lead LARS to high patient satisfaction, a shortened recovery time, an immediate restoration of stability and function, sparing of tendon stock, minimal complications, and no pain due to tendon harvesting from the patient’s body or any other iatrogenic injury.

Studies and publications support the use of LARS for all indications:

Knee (ACL) – studies and papers
Knee (PCL) – studies and papers
Knee (various) – studies and papers
Shoulder – studies and papers
Foot and ankle – studies and papers
Hip – studies and papers
Reviews
Laboratory studies and papers

Knee (ACL) – studies and papers

Gao, K. et al. (2010). Anterior Cruciate Ligament Reconstruction With LARS Artificial Ligament: A Multicenter Study With 3- to 5-Year Follow-up. Arthroscopy. The Journal of Arthroscopic and Related Surgery, Vol 26, No 4 (April), 2010: pp 515-523 R
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Hamido, F. et al. (2010). The use of the LARS artificial ligament to augment a short or undersized ACL hamstrings tendon graft. The Knee, November. [Epub ahead of print]
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Zhong-tang Liu (2009). Four-strand hamstring tendon autograft versus LARS artificial ligament for anterior cruciate ligament reconstruction. International Orthopedics, 2009 Apr 25. [Epub ahead of print]
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Fan, Q. et al. (2008). Comparison between four-strand semitendinosus tendon autograft and ligament advanced reinforcement system for anterior cruciate ligament reconstruction by arthroscopy. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Jun;22(6):676-9. P
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Khalaf, W.A (2008). Patients satisfaction after arthroscopic ACL reconstruction using the LARS artificial ligament. Available from: http://www.kneespecialty.com/acl.htm
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Cerulli, G. et al. (2007). ACL reconstruction using artificial ligaments: Five years follow-up. S.I.O.T, 33 (3suppl. 1), pp. 8238-8242 R
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Nau, T. et al. (2002). A new generation of artificial ligaments in reconstruction of the anterior cruciate ligament. Blinded prospective randomised study. JBJS (Br), Vol 84b (3), pp. 356-360 RCT
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Lavoie, P. et al. (2000). Patient satisfaction needs as related to knee stability and objective findings after ACL reconstruction using LARS artificial ligament. The Knee, 7, pp. 157-163 C
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Laboureau (1997). Symposium International de Biomatériaux Avancés (SIBA). The use of the free fibers LARS ligament in acute anterior cruciate ligament repairs
Derricks G. (1995). LARS anterior cruciate ligament reconstruction, Operative Techniques in Sports Medicine, 3(3): 187-205. C
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Knee (PCL) – studies and papers

Boisrenoult, P. et al. (2010). Reconstruction of acute posterior cruciate ligament tears using a synthetic ligament: 45 cases at five years mean follow-up. P14 - Posters: Knee – PCL (P14-1155). 14^th ESSKA Congress, June 9-12, 2010, Oslo, Norway
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Shen, G. et al.(2010). Arthroscopic Posterior Cruciate Ligament Reconstruction Using LARS Artificial Ligament: A Retrospective Study. J Surg Res. 2010 Sep 8. [Epub ahead of print]
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Li P (2008). Arthroscopic single-bundle posterior cruciate ligament reconstruction: retrospective review of hamstring tendon graft versus LARS artificial ligament.International Orthopedics, Jul: 25, R
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Brunet, P. (2005). [Reconstruction of acute posterior cruciate ligament tears using a synthetic ligament]. Rev Chir Orthop Reparatrice Appar Mot, 2005; 91(1):34-43 C
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Laboureau J.P. (2002). 10 year follow up of Acute PCL repair.SICOT Meeting – San Diego, USA.Laboureau J.P. (2002). 10 year follow up of Acute PCL repair.SICOT Meeting – San Diego, USA.
Johnson D. et al (2001). Cruciate Ligament reconstruction with Synthetics (Chap.) In Gregory C. Fanelli (2001 Ed.): Posterior Cruciate Ligament Injuries: A Practical Guide to Management, New York: Springer-Verlag, pp.189-214.
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Laboureau, J.P (2001). Reconstruction of posterior cruciate ligament rupture and posterolateral instability with synthetic ligaments. Editions Scientifiques et Medicales Elsevier SAS (Paris). Surgical Techniques in Orthopaedics and Traumatology, 2001: 55-540-C-20. C
Teule et al. (2000). Posterior Cruciate Ligament Reconstruction: The Role of Synthetic Ligaments.Riv Lt Biol Med 20. C
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Knee (various) – studies and papers

Naim S. et al. (2011). Patellar tendon reconstruction using LARS ligament: surgical technique and case report. Strategies Trauma Limb Reconstr. 2011 Apr;6(1):39-41. Epub 2011 Jan 14.
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Huang, J. et al. (2010). Cruciate ligament reconstruction using LARS artificial ligament under arthroscopy: 81 cases report. Chin Med J 2010;123(2):160-164 C
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Ranger (2010). Evaluation of reconstructive surgery using artificial ligaments in 71 acute knee dislocations
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Ibrahim, S.A. et al. (2008). Surgical management of traumatic knee dislocation.Arthroscopy 24(2), pp.178-187. C
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Ranger, P. (2008) .Treatment of acute dislocations using synthetic ligaments. Journal of Bone and Joint Surgery - British Volume, Vol 90-B, Issue SUPP_I, 113 . C
Dominikus, M. et al. (2006). Reconstructing the Extensor Apparatus with a New Polyester Ligament. Clinical Orthopaedics and Related Research, 453, pp. 328–334 P
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Talbot, M. (2004). Knee dislocations: Experience at the Hôpital du Sacré-Coeur de Montréal. Can J Surg. 2004 Feb;47(1):20-4.
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Labbe, J.L. (1999). Acute bicruciate knee injury. New Zealand Orthopaedic Association. 48^th Annual Scientific Meeting.

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Shoulder – studies and papers

Fraschini G, et al. (2010). Surgical treatment of chronic acromioclavicular dislocation: Comparison between two surgical procedures for anatomic reconstruction. Injury. [Epub ahead of print]
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Quinn, T. (2010). LARS Ligament Reconstruction for acromioclavicular joint dislocations - a clinical study. http://www.shoulderdoc.co.uk/article.asp?article=1341. Accessed in July, 2010.
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Krenn (2005). Biomechanical Analysis of Different Operative Techniques with complete ACJ disruption.Osteo Trauma Care, pp. 154-159. B
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Fialka, C (2005). Biomechanical analysis of different operative techniques for complete acromioclavicular joint disruptions
Krenn M. Revolution in shoulder prosthetics: Permanent tendon replacement for RC defect. Non sense, alternative or a solution? Jatros Orthopedica 2005:5, 11-13
Fialka, C. et al. (2004). Traumatic ACJ separation. Current concept.European Surgery Journal, 20(24). ►download abstract
Roman et al. (2003). Our experience with LARS in massive rotator cuff tear, 44 cases. EuropeanCongress of Sport Traumatology, Monte Carlo, Monaco
Fialka, C. (2000). Preliminary results in ACJ dislocation using a LARS.Poster - ESSKA 2000 (Vienna)

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Foot and ankle – studies and papers

Dhillon MS, et al. (2010). Reconstruction of bilateral spontaneous chronic idiopathic Achilles tendon rupture using LARS ligament: Case report. Foot (Edinb). 2010 Oct 21. [Epub ahead of print]
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Ibrahim, S.A. et al. (2009). Surgical treatment of Chronic Achilles Tendon Rupture. The Journal of Foot and Ankle Surgery 49(3), pp. 340-347. R
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Fletcher et al. (1997). Repair of Achilles tendon with a LARS . 1st Symposium of Biomaterial Advances, Montreal, Canada.

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Hip – studies and papers

Bajwa, AS. (2011). Gluteal tendon reconstruction in association with hip arthroplasty. Hip Int. 2011 Jun 13;21(3):288-292
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Simpson (2011). Arthroscopic Reconstruction of the Ligamentum Teres
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Holroyd, B. & Fern, D.E. (2009). Synthetic Ligaments in Hip Surgery. European Musculoskeletal Review pp. 52-54 C
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Holroyd, B. & Fern, D.E. (2008). A Novel use for Synthetic Ligaments in Hip Surgery. Annals Royal Collage of Surgery.90: pp. 253-259. C
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Reviews

Bernardino S (2010). ACL prosthesis – Any promise for the future? Knee Surg Sports Tramatol Arthrosc (2010) 18:797-804
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Legnani (2010). Anterior cruciate ligament reconstruction with synthetic grafts. A review of literature
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Chen J, Xu J, Wang A, Zheng M. Scaffolds for tendon and ligament repair: review of the efficacy of commercial products. Expert Rev Med Devices. 2009 Jan;6(1):61-73
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Mascarenhas R, MacDonald PB. Anterior cruciate ligament reconstruction: a look at prosthetics - past, present and possible future. McGill Journal of Medicine 2008, 11(1): 29-37.
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Laboratory studies and papers

Yu, S.B. et al. (2008). Histological characteristics of an ultrastructure of polyethelene terephthalate LARS ligament following the reconstruction of anterior crucate ligament in rabbits. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu. 2008;12(36):7061-7066
Trieb, K. et al. (2004). In vivo and in vitro cellular ingrowth into a new generation of artificial ligament. Eur Surg Res. May-Jun;36(3):148-51.
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Hagemeister, N. et al (2002). Comparison of two methods for reconstruction of the posterior cruciate ligament using a computer based method: quantitative evaluation of laxity, three-dimensional kinematics and ligament deformation measurement in cadaver knees, The Knee, 9(4): 291-299.
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Tabrizian M., et al. (1996)., Technical report: Evaluation of synthetic LARS knee ligaments, Biomechanics and Biomaterials Research Group, École Polytechnique de Montréal, pp.1-34.

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Important: LARS is not available or cleared for distribution in all international markets. For more details, please contact your local subsidiary or distributor by visiting the Corin worldwide section of the Corin Group corporate website.

New paper

Evaluation of reconstructive surgery using artifical ligaments in 71 acute knee dislocations

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